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  • 產(chǎn)品名稱：MatrixMetallopeptidase3(Stromelysin1,Progelatinase)(MMP3)(MiddleRegion)Peptide

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MatrixMetallopeptidase3(Stromelysin1,Progelatinase)(MMP3)(MiddleRegion)Peptide
詳情介紹：
Blocked Antibody anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (Middle Region) antibody (ABIN2777122)
Characteristics This is a synthetic peptide designed for use in combination with anti-MMP3 antibody (Catalog #: ARP42042_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background MMP3 can degrade fibronectin, laminin, gelatins of type I, III, IV, and V, collagens III, IV, X, and IX, and cartilage proteoglycans. MMP3 activates procollagenase.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alias Symbols: MGC126102, MGC126103, MGC126104, MMP-3, SL-1, STMY, STMY1, STR1, CHDS6

Protein Interaction Partner: ACAN,BCAN,CCL13,CCL2,CCL7,CCL8,DCN,HAPLN1,IGFBP3,MMP3,PLG,SERPINE1,SPOCK1,SPOCK3,SPP1,TIMP1,TIMP3,TNFSF11,BCAN,SPOCK3,TIMP1

Protein Size: 477
Molecular Weight 43 kDa
Gene ID 4314
NCBI Accession NM_002422, NP_002413
UniProt P08254
Research Area Angiogenesis, Proteolysis / Ubiquitin, Extracellular Matrix, Cardiovascular, Atherosclerosis, Matrix Metalloproteinases, Metalloprotease
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.