產(chǎn)品詳情

  • 產(chǎn)品名稱：Ubiquitin-Like,ContainingPHDandRINGFingerDomains,1(UHRF1)(C-Term)Peptide

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  • 產(chǎn)品廠商：半導(dǎo)體
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簡單介紹：
Ubiquitin-Like,ContainingPHDandRINGFingerDomains,1(UHRF1)(C-Term)Peptide
詳情介紹：
Blocked Antibody anti-UHRF1 antibody (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1) (C-Term) (ABIN2779741)
Sequence DDEPGPWTKE GKDRIKKLGL TMQYPEGYLE ALANREREKE NSKREEEEQQ
Characteristics This is a synthetic peptide designed for use in combination with anti-UHRF1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.

Protein Size: 793
Molecular Weight 90 kDa
Gene ID 29128
UniProt Q96T88
Research Area Chromatin and Nuclear Signaling, Transcription Factors, Chromatin Binding Proteins
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeat freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.