產(chǎn)品詳情

  • 產(chǎn)品名稱：ProteinPhosphatase1,CatalyticSubunit,alphaIsoform(PPP1CA)(C-Term)Peptide

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  • 產(chǎn)品廠商：半導(dǎo)體
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簡單介紹：
ProteinPhosphatase1,CatalyticSubunit,alphaIsoform(PPP1CA)(C-Term)Peptide
詳情介紹：
Blocked Antibody anti-Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA) (C-Term) antibody (ABIN2789191)
Sequence RQLVTLFSAP NYCGEFDNAG AMMSVDETLM CSFQILKPAD KNKGKYGQFS
Characteristics This is a synthetic peptide designed for use in combination with anti-Ppp1ca Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background Ppp1ca is a protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Regulates NEK2 function in terms of kinase activity and centrosome number and splitting, both in the presence and absence of radiation-induced DNA damage. Regulator of neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development.

Alias Symbols: Ppp1c, dism2

Protein Size: 330
Molecular Weight 37 kDa
Gene ID 19045
NCBI Accession NM_031868, NP_114074
UniProt P62137
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeat freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.