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  • 產(chǎn)品名稱(chēng)：Platelet-DerivedGrowthFactorC(PDGFC)(N-Term)Peptide

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Platelet-DerivedGrowthFactorC(PDGFC)(N-Term)Peptide
詳情介紹：
Blocked Antibody anti-PDGFC antibody (Platelet-Derived Growth Factor C) (N-Term) (ABIN2788903)
Sequence MLLLGLLLLT SALAGQRTGT RAESNLSSKL QLSSDKEQNG VQDPRHERVV
Characteristics This is a synthetic peptide designed for use in combination with anti-Pdgfc Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling. Plays an important role in angiogenesis and blood vessel development. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function.

Alias Symbols: 1110064L01Rik, AI647969, PDGF-C

Protein Size: 345
Molecular Weight 39 kDa
Gene ID 54635
NCBI Accession NM_019971, NP_064355
UniProt Q8CI19
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeat freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.