產(chǎn)品詳情

  • 產(chǎn)品名稱：NuclearFactor(Erythroid-Derived2),45kDa(NFE2)(C-Term)Peptide

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簡單介紹：
NuclearFactor(Erythroid-Derived2),45kDa(NFE2)(C-Term)Peptide
詳情介紹：
Blocked Antibody anti-NFE2 antibody (Nuclear Factor (Erythroid-Derived 2), 45kDa) (C-Term) (ABIN2777229)
Sequence ARGEADRTLE VMRQQLAELY HDIFQHLRDE SGNSYSPEEY VLQQAADGAI
Characteristics This is a synthetic peptide designed for use in combination with anti-Nfe2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background Nfe2 is a component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation.It binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. It requires MAFK or other small MAF proteins for binding to the NF-E2 motif. It may play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

Alias Symbols: 45?kDa, NF-E2, p45, p45NFE2, p45nf-e2

Protein Size: 373
Molecular Weight 41 kDa
Gene ID 18022
NCBI Accession NM_008685, NP_032711
UniProt Q07279
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeat freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.