產(chǎn)品詳情

  • 產(chǎn)品名稱：TAF5-LikeRNAPolymeraseII,P300/CBP-AssociatedFactor(PCAF)-AssociatedFactor,65kDa

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  • 產(chǎn)品廠商：半導(dǎo)體
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TAF5-LikeRNAPolymeraseII,P300/CBP-AssociatedFactor(PCAF)-AssociatedFactor,65kDa(TAF5L)(N-Term)Peptide
詳情介紹：
Blocked Antibody anti-TAF5-Like RNA Polymerase II, P300/CBP-Associated Factor (PCAF)-Associated Factor, 65kDa (TAF5L) (N-Term) antibody (ABIN2777471)
Sequence FVYLHLNLVQ NSPKSTVESF YSRFHGMFLQ NASQKDVIEQ LQTTQTIQDI
Characteristics This is a synthetic peptide designed for use in combination with anti-TAF5L Antibody(ARP31877_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF5L encodes a protein that is a component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs, TAF5. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation.

Alias Symbols: PAF65B

Protein Interaction Partner: ATXN7L3,CEBPE,KAT2B,MYC,SUPT3H,TAF10,TAF9,USP22

Protein Size: 325
Molecular Weight 37 kDa
Gene ID 27097
NCBI Accession NM_001025247, NP_001020418
Research Area Transcription Factors, Chromatin and Nuclear Signaling
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.