產(chǎn)品詳情
簡單介紹:
RetinalGProteinCoupledReceptor(RGR)(C-Term)Peptide
詳情介紹:
Blocked Antibody | anti-RGR antibody (Retinal G Protein Coupled Receptor) (C-Term) (ABIN2789477) |
Sequence | GKSGHLQVPA LIAKMVPTIN AINYALGNEM VCRGIWQCLS PQKREKDRTK |
Characteristics | This is a synthetic peptide designed for use in combination with anti-RGR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. |
Purification | Purified |
Background |
This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alias Symbols: RP44 Protein Interaction Partner: KIAA1279,RDH5,KIAA1279 Protein Size: 253 |
Molecular Weight | 28 kDa |
Gene ID | 5995 |
NCBI Accession | NM_001012722, NP_001012740 |
Research Area | Neurology |
Application Notes | Each Investigator should determine their own optimal working dilution for specific applications. |
Restrictions | For Research Use only |
Format | Lyophilized |
Reconstitution | Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS. |
Concentration | 1 mg/mL |
Buffer | Final peptide concentration is 1 mg/mL in PBS. |
Handling Advice | Avoid repeated freeze-thaw cycles. |
Storage | -20 °C |
Storage Comment | For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |