產(chǎn)品詳情
簡(jiǎn)單介紹:
rPhrixotoxin-1
詳情介紹:
Sequence | YCQKWMWTCD SARKCCEGLV CRLWCKKII. |
Specificity | Phrixotoxin-1 blocks specifically and reversibly Kv4.2 and Kv4.3 channels1. |
Characteristics |
Source: Phrixotrichus auratus (Chilean copper tarantula). Molecular formula: C156H239N44O37S7. Disulfide bonds between Cys2-Cys16, Cys9-Cys21, and Cys15-Cys25. |
Purity | > 98 % |
Molecular Weight | 3549 |
Application Notes | 10-100 nM |
Comment |
k-theraphotoxin-Ps1a, k-TRTX-Ps1a, PaTX1 |
Restrictions | For Research Use only |
Format | Lyophilized |
Reconstitution |
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min). Concentration after reconstitution: Dissolving 50g in 1.409 ml will provide a stock solution of 10 M. |
Handling Advice | Soluble in Water. |
Product cited in: |
Chagot, Escoubas, Villegas, Bernard, Ferrat, Corzo, Lazdunski, Darbon: "Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratus." in: Protein science : a publication of the Protein Society, Vol. 13, Issue 5, pp. 1197-208, 2004 (PubMed).
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