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  • 產(chǎn)品名稱：Rabbitanti-HumanIgG(LightChain)Antibody(HRP)

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簡單介紹：
Rabbitanti-HumanIgG(LightChain)Antibody(HRP)
詳情介紹：
Immunogen Human igg light chain protein
Isotype IgG
Purification Caprylic Acid Ammonium Sulfate Precipitation
Background Serum immunoglobulin IgG is the main component, accounting for total serum immunoglobulin content of 75 %. 40 ~ 50 % of the distribution in the serum, and the remaining distributed in the organization. Molecular weight of about 150 kDa. Human serum IgG mainly single, normal, including four subtypes of IgG, IgG1 accounted for its 60 ~ 70 %, IgG2 accounted for 15 ~ 20 %, IgG3 accounted for 5 ~ 10 %, IgG4 accounts for 1 ~ 7 %. These subtypes in the classical pathway of complement activation in the binding capacity varies. IgG mainly by the spleen and lymph nodes in the synthesis of plasma cells, is the only antibodies through the placenta, to prevent birth within weeks of infection play a significant role. Newborn infants after 3 months has been able to synthesize IgG, 2 ~ 3 years old has reached ***** levels. Decreased gradually after the age of 40. IgG content of individual differences, the same individual under different conditions, fluctuations are also high. Antigen stimulation in the body produces most of the anti-bacterial, anti-virus, anti-toxin antibodies are IgG. Many autoantibodies, such as systemic lupus erythematosus LE factor, anti-thyroglobulin antibodies are IgG. IgG is the body's main anti-infection immune antibodies.
Molecular Weight 150 kDa
Research Area Immunology, Secondary Antibodies
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Restrictions For Research Use only
Format Liquid
Buffer 0.03 % Proclin 300, 50 % Glycerol, 0.01 M PBS, pH 7.4
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice Avoid freeze and thaw cycles.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Storage -20 °C
Storage Comment Shipped at 4 °C. Upon delivery aliquot and store at -24 °C or -84 °C.