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  • 產(chǎn)品名稱:Mouseanti-HumanlambdaLightChain(Lambda-IgLC)Antibody

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簡單介紹:
Mouseanti-HumanlambdaLightChain(Lambda-IgLC)Antibody
詳情介紹:
Immunogen Purified human lambda light chain was used as the immunogen for this Lambda Light Chain antibody.
Clone LLC-1738
Isotype Kappa, IgG1
Purification Protein G affinity chromatography
Alternative Name Lambda Light Chain
Background This mAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with kappa light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Application Notes The optimal dilution of the Lambda Light Chain antibody for each application should be determined by the researcher.\. Flow Cytometry: 0.5-1?μg/million cells in 0.1ml,Immunofluorescence: 1-2?μg/mL,Western blot: 0.5-1?μg/mL,Immunohistochemistry (FFPE): 0.5-1?μg/mL for 30?minutes at RT
Restrictions For Research Use only
Buffer 0.2?mg/mL in 1X PBS with 0.1?mg/mL BSA (US sourced) and 0.05?% sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store the Lambda Light Chain antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).