產(chǎn)品詳情
所在位置: 首頁> 產(chǎn)品目錄> 二抗>

  • 產(chǎn)品名稱：Mouseanti-HumanlambdaLightChain(Lambda-IgLC)Antibody

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：NSJBio
  • 產(chǎn)品文檔：
你添加了1件商品 查看購物車
簡單介紹：
Mouseanti-HumanlambdaLightChain(Lambda-IgLC)Antibody
詳情介紹：
Immunogen Purified human lambda light chain was used as the immunogen for the anti-Lambda Light Chain antibody.
Clone Lamb14
Isotype IgG2a, kappa
Characteristics This mAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Purification Protein G affinity chromatography
Alternative Name lambda Light Chain
Background This mAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Application Notes Optimal dilution of the anti-Lambda Light Chain antibody should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10?mM Citrate buffer,?pH 6.0, for 10-20?min followed by cooling at RT for 20?min
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30?min.\. Flow Cytometry: 0.5-1?μg/million cells in 0.1ml,Immunofluorescence: 1-2?μg/mL,Western blot: 0.5-1?μg/mL,Immunohistochemistry (FFPE): 0.5-1?μg/mL for 30?min at RT (1),Prediluted format : incubate for 30?min at RT (2)
Restrictions For Research Use only
Concentration 0.2 mg/mL
Buffer 0.2?mg/mL in 1X PBS with 0.1?mg/mL BSA (US sourced) and 0.05?% sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store the anti-Lambda Light Chain antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Supplier Images
Immunohistochemistry (IHC) image for Mouse anti-Human lambda Light Chain (Lambda-IgLC) antibody (ABIN3026850) Formalin-fixed, paraffin-embedded human tonsil stained with anti-Lambda Light Chain a...
Western Blotting (WB) image for Mouse anti-Human lambda Light Chain (Lambda-IgLC) antibody (ABIN3026850) Western blot of human Intestinal lysate using anti-Lambda Light Chain antibody (Lamb14).