產(chǎn)品詳情

  • 產(chǎn)品名稱：Mouseanti-HumanIgMHeavyChainAntibody

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  • 產(chǎn)品廠商：NSJBio
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Mouseanti-HumanIgMHeavyChainAntibody
詳情介紹：
Immunogen Recombinant heavy chain of human IgM was used as the immunogen for this antibody.
Clone IM373
Isotype IgG1, kappa
Characteristics This antibody recognizes a protein of 75 kDa, identified as the mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. The antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Purification Protein G affinity chromatography
Background This antibody recognizes a protein of 75?kDa, identified as the mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. The antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Gene ID 3507
Application Notes The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10?mM citrate buffer,?pH 6.0, for 10-20?min followed by cooling at RT for 20?minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30?min.\. FACS: 0.5-1?μg/million cells,IF: 0.5-1?μg/mL,WB: 0.5-1?μg/mL,IHC (Frozen): 0.5-1?μg/mL for 30?minutes at RT (1),Prediluted format : incubate for 30?min at RT (2)
Restrictions For Research Use only
Concentration 0.2 mg/mL
Buffer 0.2?mg/mL in 1X PBS with 0.1?mg/mL BSA (US sourced) and 0.05?% sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store the IgM heavy chain antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Supplier Images
Immunohistochemistry (IHC) image for Mouse anti-Human IgM Heavy Chain antibody (ABIN3026664) IHC testing of human tonsil stained with IgM heavy chain antibody.
Immunohistochemistry (IHC) image for Mouse anti-Human IgM Heavy Chain antibody (ABIN3026664) IHC testing of human tonsil stained with IgM heavy chain antibody.
Western Blotting (WB) image for Mouse anti-Human IgM Heavy Chain antibody (ABIN3026664) Western blot testing of Raji cell lysate with IgM heavy chain antibody.