產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：Mouseanti-HumanIgEAntibody(Biotin)

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  • 產(chǎn)品廠商：NBS-C
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Mouseanti-HumanIgEAntibody(Biotin)
詳情介紹：
Immunogen purified human myeloma IgE
Clone BSW17-NBS01
Isotype IgG1 kappa
Specificity Human IgE, Fce3-4, no cross-ractivity with other human or murine Ab isotypes
Sensitivity Reactivity > 95 %, compared to calibrator (Internal Standard mAb clone BSW17), tested by ELISA binding to immobilized human Standard IgE (clone: SUS-11)
Characteristics IGHE, chromosome 14q32.33
Purification Affinity - purified from cell culture supernatant by Immunoaffinity Chromatography on CH-Sepharose 4B - rat monoclonal anti- mouse Ck
Purity > 85 %, tested by analytical Gel Permeation Chromatography
Sterility Sterile filtered
Background The antibody recognizes a conformational epitope within the Ce3 domain of human IgE spanning towards the amino-terminal part of the Ce4 domain. It blocks the binding of IgE to its high affinity receptor on mast cells and basophils. It is therefore suited as an inhibitory reference compound for mast cell modulator profiling and basic research on IgE mediated mast cell receptor signaling.
Research Area Immunology, Secondary Antibodies
Application Notes Sterile filtered solution, does not contain Na-azide. Recommended for functional cellular assays (mast cell / basophil activation).
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer PBS, pH=7.2, sterile filtered, contains no NaN3
Handling Advice Aliquot to Avoid repeated freezing and thawing.
Storage 4 °C
Supplier Images
image for Mouse anti-Human IgE antibody (Biotin) (ABIN457504) product purity: gel permeation chromatography (Superose 12/HR)
ELISA image for Mouse anti-Human IgE antibody (Biotin) (ABIN457504) ELISA binding to human IgE(SUS-11), Detection: Streptavidin-HRP