產(chǎn)品詳情
簡單介紹:
PLX4720
詳情介紹:
Purpose | PLX4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), 10-fold selectivity for B-RafV600E than wild-type B-Raf. |
Characteristics |
Target: Raf inhibitor Receptor: B-Raf |
Purification | All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality. |
Purity | 97.80?% |
Formula | C17H14ClF2N3O3S |
Solubility | Soluble in DMSO |
Molecular Weight | 413.83 g/mol |
CAS-No | 918505-84-7 |
Application Notes | Optimal working dilution should be determined by the investigator. |
Restrictions | For Research Use only |
Format | Solid |
Storage | -20 °C |
Storage Comment |
For the majority of compounds, they could be dissolved in DMSO or other organic solvent. Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience. Several freeze/thaw cycles should not damage the activity of our small molecule products. However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours. |
Expiry Date | 24 months |