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Lenalidomide(CC-5013)
詳情介紹:
Purpose Lenalidomide (initially known as CC-5013 and marketed as Revlimid? by Celgene) is a derivative of thalidomide introduced in 2004. It was initially intended as a treatment for multiple myeloma, for which thalidomide is an accepted therapeutic modality, but has also shown efficacy in the hematological disorders known as the myelodysplastic syndromes. FDA approved on December 27, 2005.
Characteristics Source of Compound: synthetic
Target: TNF-alpha inhibitor, Cadherin inhibitor
Receptor: TNF-α,Cadherin-5,Prostaglandin G/H synthase ,CRBN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 99?%
Formula C13H13N3O3
Solubility DMSO 52 mg/mL,Water <1 mg="" ml="" <="" td="">
Molecular Weight 259.26 g/mol
CAS-No 191732-72-6
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months