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  • 產(chǎn)品名稱：JNJ-26854165(Serdemetan)

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簡單介紹：
JNJ-26854165(Serdemetan)
詳情介紹：
Purpose JNJ-26854165 (Serdemetan) acts as a HDM2 ubiquitin ligase antagonist and also induces early apoptosis in p53 wild-type cells, inhibits cellular proliferation followed by delayed apoptosis in the absence of functional p53. Phase 1.
Characteristics Tradename: Serdemetan
Target: p53 activator, E3 ligase inhibitor, Mdm2 inhibitor
Receptor: p53,HDM2,Mdm2
Status: INN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 97?% +
Formula C21H20N4
Solubility 200 mM in DMSO
Molecular Weight 328.42 g/mol
CAS-No 881202-45-5
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months