Purpose
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Lenvatinib (E7080) is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β in cell-free assays. Phase 3.
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Characteristics
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Target: VEGFR inhibitor Receptor: VEGFR2/KDR,VEGFR3/FLT4,VEGFR1/FLT1,PDGFRβ
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Purification
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All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
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Purity
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98?%
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Formula
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C21H19ClN4O4
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Solubility
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100 mM in DMSO
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