產(chǎn)品詳情

  • 產(chǎn)品名稱：VX-680(Tozasertib,MK-0457)

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：TargetMol
  • 產(chǎn)品文檔：
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VX-680(Tozasertib,MK-0457)
詳情介紹：
Purpose VX-680 (Tozasertib, MK-0457) is a pan-Aurora inhibitor, mostly against Aurora A with Kiapp of 0.6 nM in a cell-free assay, less potent towards Aurora B/Aurora C and 100-fold more selective for Aurora A than 55 other kinases. Phase 2.
Characteristics Target: Aurora Kinase inhibitor
Receptor: Aurora A,Aurora C,Aurora B, FLT3,Bcr-Abl
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 99.60?%
Formula C23H28N8OS
Solubility 200 mM in DMSO
Molecular Weight 464.59 g/mol
CAS-No 639089-54-6
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months