產(chǎn)品詳情

  • 產(chǎn)品名稱：PF06463922

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：TargetMol
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
PF06463922
詳情介紹：
Purpose PF-06463922 is a potent, dual ALK/ROS1 inhibitor with Ki of <0.02 nm,="" <0.07="" and="" 0.7="" nm="" for="" ros1,="" alk="" (wt),="" (l1196m),="" respectively.="" phase="" 1.="" <="" td="">
Characteristics Tradename: PF-06463922
Target: TGF-beta/Smad inhibitor, ROS
Receptor: ROS1,ALLK,LTK,FER,FES,FAK2
Status: Experimental
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 100?%
Formula C21H19FN6O2
Solubility DMSO 81 mg/Ml, Ethanol 30 mg/mL warmed
Molecular Weight 406.41 g/mol
CAS-No 1454846-35-5
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months