產(chǎn)品詳情

  • 產(chǎn)品名稱：Regorafenib(BAY73-4506)

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  • 產(chǎn)品廠商：TargetMol
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簡(jiǎn)單介紹：
Regorafenib(BAY73-4506)
詳情介紹：
Purpose Regorafenib (BAY 73-4506) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively.
Characteristics Target: VEGFR inhibitor, PDGFR inhibitor, FGFR inhibitor, Raf inhibitor
Receptor: VEGFR1/2/3,PDGFRβ,FGFR, Raf-1/B-Raf
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 98?%
Formula C21H15ClF4N4O3
Solubility DMSO > 100mM
Molecular Weight 482.82 g/mol
CAS-No 755037-03-7
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months