產(chǎn)品詳情
簡(jiǎn)單介紹:
Clofarabine
詳情介紹:
Purpose | Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed in the U.S. and Canada as Clolar. In Europe and Australia/New Zealand the product is marketed under the name Evoltra. Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed. It is not known if the drug extends life expectancy. Some investigations of effectiveness in cases of acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) have been carried out. |
Characteristics |
Tradename: CLOLAR Source of Compound: synthetic Target: RNA Synthesis Receptor: Ribonucleotide reductase Status: USP |
Purification | All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality. |
Purity | 99?% |
Formula | C10H11ClFN5O3 |
Solubility | Soluble in DMSO > 10 mM |
Molecular Weight | 303.68 g/mol |
CAS-No | 123318-82-1 |
Application Notes | Optimal working dilution should be determined by the investigator. |
Restrictions | For Research Use only |
Format | Solid |
Storage | -20 °C |
Storage Comment |
For the majority of compounds, they could be dissolved in DMSO or other organic solvent. Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience. Several freeze/thaw cycles should not damage the activity of our small molecule products. However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours. |
Expiry Date | 24 months |