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  • 產(chǎn)品名稱：Crizotinib(PF-02341066)

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  • 產(chǎn)品廠商：TargetMol
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Crizotinib(PF-02341066)
詳情介紹：
Purpose Crizotinib an inhibitor of receptor tyrosine kinase for the treatment of non-small cell lung cancer (NSCLC). Verification of the presence of ALK fusion gene is done by Abbott Molecular's Vysis ALK Break Apart FISH Probe Kit. This verification is used to select for patients suitable for treatment. FDA approved in August 26, 2011.
Characteristics Tradename: XALKORI
Source of Compound: synthetic
Target: TGF-beta/Smad inhibitor,c-MET inhibitor
Receptor: ALK ,c-MET
Status: USP
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 99?% +
Formula C21H22Cl2FN5O
Solubility DMSO 9 mg/mL,Water <1 mg="" ml="" <="" td="">
Molecular Weight 450.34 g/mol
CAS-No 877399-52-5
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months