Purpose
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OSI-930 is a potent inhibitor of Kit, KDR and CSF-1R with IC50 of 80 nM, 9 nM and 15 nM, respectively, also potent to Flt-1, c-Raf and Lck and low activity against PDGFRα/β, Flt-3 and Abl. Phase 1.
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Characteristics
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Target: CSF-1R inhibitor,c-Kit inhibitor, Raf inhibitor, PDGFR inhibitor,FLT3 inhibitor Receptor: FLT1/KDR/CSF-1R/LCK/C-Raf/Kit/FLT3/PDGFRα/Abl
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Purification
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All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
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Purity
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98.77?%
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Formula
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C22H16F3N3O2S
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Solubility
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200 mM in DMSO
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