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  • 產(chǎn)品名稱：Canertinib2HCl

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  • 產(chǎn)品廠商：TargetMol
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Canertinib2HCl
詳情介紹：
Purpose Canertinib Dihydrochloride is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and radiosensitizing activities. Canertinib binds to the intracellular domains of epidermal growth factor receptor tyrosine kinases (ErbB family), irreversibly inhibiting their signal transduction functions and resulting in tumor cell apoptosis and suppression of tumor cell proliferation. This agent also acts as a radiosensitizing agent and displays synergistic activity with other chemotherapeutic agents.
Characteristics Target: EGFR inhibitor, HER2 inhibitor
Receptor: EGFR, ErbB2
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 100?%
Formula C24H27Cl3FN5O3
Solubility Soluble in DMSO
Molecular Weight 558.86 g/mol
CAS-No 289499-45-2
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months