Purpose
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Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of its class approved for this use by the U.S. Food and Drug Administration. As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use.
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Characteristics
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Tradename: Aloxi Source of Compound: synthetic Target: 5-HT Receptor antagonist Receptor: 5-HT Receptor Status: USP,
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Purification
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All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
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Purity
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99.00?%
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Formula
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C19H24N2O.HCl
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Solubility
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Water 67 mg/mL, DMSO <1 mg="" ml="" <="" td="">
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