Purpose
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Potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor. Also inhibits cellular receptor phosphorylation of FLT3, RET and CSF-1R. Exhibits antiangiogenic and antitumor activity in multiple xenograft models.
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Characteristics
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Tradename: SUTENT Source of Compound: synthetic Target: c-Kit inhibitor, PDGFR inhibitor, VEGFR inhibitor Receptor: c-Kit,PDGFRβ,VEGFR2 Status: USP
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Purification
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All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
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Purity
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98?%
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Formula
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C22H27FN4O2
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Solubility
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Soluble in DMSO
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