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  • 產(chǎn)品名稱：Brinzolamide

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  • 產(chǎn)品廠商：TargetMol
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Brinzolamide
詳情介紹：
Purpose Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase inhibitor. Carbonic anhydrase (CA) is an enzyme found in many tissues of the body including the eye. It catalyzes the reversible reaction involving the hydration of carbon dioxide and the dehydration of carbonic acid. In humans, carbonic anhydrase exists as a number of isoenzymes, the most active being carbonic anhydrase II (CA-II). Inhibition of carbonic anhydrase in the ciliary processes of the eye decreases aqueous humor secretion, presumably by slowing the formation of bicarbonate ions with subsequent reduction in sodium and fluid transport. The result is a reduction in intraocular pressure. Brinzolamide is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Characteristics Tradename: AZOPT
Source of Compound: synthetic, AL-4682
Target: Carbonic anhydrase inhibitor
Receptor: CA
Status: USP, INN, BAN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 99?%
Formula C12H21N3O5S3
Solubility DMSO: 77 mg/mL (200.77 mM)
Molecular Weight 383.51 g/mol
CAS-No 138890-62-7
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months