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  • 產(chǎn)品名稱：BMS-777607

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BMS-777607
詳情介紹：
Purpose BMS-777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50 of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM in cell-free assays, 40-fold more selective for Met-related targets versus Lck, VEGFR-2, and TrkA/B, and more than 500-fold greater selectivity versus all other receptor and non receptor kinases. Phase 1/2.
Characteristics Target: c-Met inhibitor,TAM Receptor inhibitor
Receptor: c-Met,Axl,Ron,Tyro3,Mer, FLT3, Aurora B, LCK, VEGFR2, TrkB, TrkA, PKA, BTK
Status: experimental
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 100?%
Formula C25H19ClF2N4O4
Solubility 100 mM in DMSO
Molecular Weight 512.89 g/mol
CAS-No 1025720-94-8
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months