產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：Zidovudine

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：TargetMol
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
Zidovudine
詳情介紹：
Purpose A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia.
Characteristics Tradename: RETROVIR
Source of Compound: synthetic, AZT, BW-A509U
Target: Reverse Transcriptase inhibitor
Receptor: Reverse Transcriptase, Telomerase reverse transcriptase
Status: USP, INN, BAN, JAN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 98?%
Formula C10H13N5O4
Solubility Soluble in water
Molecular Weight 267.24 g/mol
CAS-No 30516-87-1
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months