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  • 產(chǎn)品名稱：Sildenafil

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簡單介紹：
Sildenafil
詳情介紹：
Purpose Sildenfail is a vasoactive agent used to treat erectile dysfunction and reduce symptoms in patients with pulmonary arterial hypertension (PAH). Sildenafil elevates levels of the second messenger, cGMP, by inhibiting its breakdown via phosphodiesterase type 5 (PDE5). PDE5 is found in particularly high concentrations in the corpus cavernosum, erectile tissue of the penis. It is also found in the retina and vascular endothelium. Increased cGMP results in vasodilation which facilitates generation and maintenance of an erection. The vasodilatory effects of sildenafil also help reduce symptoms of PAH.
Characteristics Tradename: VIAGRA
Source of Compound: synthetic, UK-92480-10
Target: PDE inhibitor
Receptor: PDE5, PDE6
Status: USAN, INN, BAN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 99?%
Formula C28H38N6O11S
Solubility Water:3.5 mg/mL
Molecular Weight 474.58 g/mol
CAS-No 139755-83-2
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months