產(chǎn)品詳情
簡單介紹:
Zonisamide
詳情介紹:
Purpose | Zonisamide is a sulfonamide anticonvulsant approved for use as an adjunctive therapy in *****s with partial-onset seizures. Zonisamide may be a carbonic anhydrase inhibitor although this is not one of the primary mechanisms of action. Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels leading to a reduction of T-type calcium channel currents, or by binding allosterically to GABA receptors. This latter action may inhibit the uptake of the inhibitory neurotransmitter GABA while enhancing the uptake of the excitatory neurotransmitter glutamate. |
Characteristics |
Tradename: ZONEGRAN Source of Compound: synthetic Target: Carbonic anhydrase inhibitor,Calcium Channel inhibitor,Sodium Channel inhibitor Receptor: CA,Calcium Channel,Sodium channel Status: USP |
Purification | All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality. |
Purity | 98?% |
Formula | C8H8N2O3S |
Solubility | Soluble in DMSO |
Molecular Weight | 212.23 g/mol |
CAS-No | 68291-97-4 |
Application Notes | Optimal working dilution should be determined by the investigator. |
Restrictions | For Research Use only |
Format | Solid |
Storage | -20 °C |
Storage Comment |
For the majority of compounds, they could be dissolved in DMSO or other organic solvent. Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience. Several freeze/thaw cycles should not damage the activity of our small molecule products. However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours. |
Expiry Date | 24 months |