Purpose
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Zonisamide is a sulfonamide anticonvulsant approved for use as an adjunctive therapy in *****s with partial-onset seizures. Zonisamide may be a carbonic anhydrase inhibitor although this is not one of the primary mechanisms of action. Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels leading to a reduction of T-type calcium channel currents, or by binding allosterically to GABA receptors. This latter action may inhibit the uptake of the inhibitory neurotransmitter GABA while enhancing the uptake of the excitatory neurotransmitter glutamate.
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Characteristics
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Tradename: ZONEGRAN Source of Compound: synthetic Target: Carbonic anhydrase inhibitor,Calcium Channel inhibitor,Sodium Channel inhibitor Receptor: CA,Calcium Channel,Sodium channel Status: USP
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Purification
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All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
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Purity
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98?%
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Formula
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C8H8N2O3S
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Solubility
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Soluble in DMSO
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