Purpose
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Motesanib is an orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-derived growth factor (PDGFR), Kit, and Ret receptors, thereby inhibiting angiogenesis and cellular proliferation.
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Characteristics
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Target: VEGFR inhibitor, c-Kit inhibitor, PDGFR inhibitor Receptor: VEGFR1,VEGFR2,VEGFR2/Flk1,VEGFR3,Kit,RET,PDGFR
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Purification
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All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
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Purity
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97?% +
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Formula
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C22H23N5O
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Solubility
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100 mM in DMSO
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