產(chǎn)品詳情

  • 產(chǎn)品名稱：FG-4592

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
FG-4592
詳情介紹：
Characteristics

PubChem CID: 11256664
Molecular Formula: C??H??N?O?
Cell Premeable: Yes

Salt form: No

FG-4592 is an inhibitor of hypoxia inducible factor (HIF) prolyl hydroxylase, potentially useful for the treatment of anemia. FG-4592 stabilizes the activities of HIF, a cytosolic transcription factor, leading to activation of the genes associated with erythropoiesis, including erythropoietin and enzymes involved in iron metabolism.

Smiles: CC1=NC(=C(C2=C1C=C(C=C2)OC3=CC=CC=C3)O)C(=O)NCC(=O)O

InChi: InChI=1S/C19H16N2O5/c1-11-15-9-13(26-12-5-3-2-4-6-12)7-8-14(15)18(24)17(21-11)19(25)20-10-16(22)23/h2-9,24H,10H2,1H3,(H,20,25)(H,22,23)

Inchi Key: YOZBGTLTNGAVFU-UHFFFAOYSA-N
Purity ≥ 98?% by HPLC
Chemical Name N-[(4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]-glycine; ASP1517; Roxadustat
Formula C??H??N?O?
Permeability Cell-permeable
Background Synonyms: N-[(4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]-glycine, ASP1517, Roxadustat
Molecular Weight 352.4 g/mol
CAS-No 808118-40-3
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 36 months