產(chǎn)品詳情

  • 產(chǎn)品名稱：AMMCiodide

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
AMMCiodide
詳情介紹：
Purpose A useful substrate for human cytochrome P450 CYP2D6
Characteristics AMMC iodide is a useful substrate for the human cytochrome P450 CYP2D6 isozyme. It is demethylated to the fluorescent product 3-[2-(N,N-diethyl-N-methyl ammonium)ethyl]-7-hydroxy-4-methylcoumarin (AMHC). After the AMMC is hydrolyzed, the pH is increased by addition of base for optimal fluorescence detection. AMMC has been used with human liver microsomes to determine CYP2D6 activity and inhibition.
Purity ≥ 98?% by NMR
Chemical Name 3-[2-(N,N-diethyl-N-methylammonium)ethyl]-7-methoxy-4-methylcoumarin iodide
Formula C??H??INO?
Permeability Not-permeable
Solubility Acetonitrile
Molecular Weight 431.31 g/mol
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months