產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：CB5083

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
CB5083
詳情介紹：
Characteristics

PubChem CID: 73051434
Molecular Formula: C??H??N?O?
Cell Premeable: Yes

Salt form: No

CB5083 is a potent, ATP-competitive, D2-selective, p97 inhibitor (IC?? = 11 nM). In xenograft models, CB-5083 causes modulation of key p97-related pathways, induces apoptosis, and has antitumor activity in a broad range of both hematological and solid tumor models.

Smiles: CC1=CC2=C(C=CC=C2N1C3=NC4=C(COCC4)C(=N3)NCC5=CC=CC=C5)C(=O)N

InChi: InChI=1S/C24H23N5O2/c1-15-12-18-17(22(25)30)8-5-9-21(18)29(15)24-27-20-10-11-31-14-19(20)23(28-24)26-13-16-6-3-2-4-7-16/h2-9,12H,10-11,13-14H2,1H3,(H2,25,30)(H,26,27,28)

Inchi Key: RDALZZCKQFLGJP-UHFFFAOYSA-N
Purity ≥ 98?% by HPLC
Chemical Name 1-(4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide
Formula C??H??N?O?
Permeability Cell-permeable
Background Synonyms: 1-(4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide
Molecular Weight 413.47 g/mol
CAS-No 1542705-92-9
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months