產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：7BIO

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
7BIO
詳情介紹：
Characteristics

PubChem CID: 11846148
Molecular Formula: C??H??BrN?O?
Cell Premeable: Yes

Salt form: No

7BIO is a caspase- independent nonapoptotic cell death inducer. Also acts as an ATP-competitive FLT3 inhibitor and DYRK1A and DYRK 2 (Dual-specificity tyrosine phosphorylation-regulated kinase) inhibitor. In addition, 7BIO is a necrosis inducer and inflammasome activator. Also a potent inhibitor of Aurora kinase B and C.

Smiles: C1=CC=C2C(=C1)C(=C(N2)C3=C4C=CC=C(C4=NC3=O)Br)NO

InChi: InChI=1S/C16H10BrN3O2/c17-10-6-3-5-9-12(16(21)19-13(9)10)15-14(20-22)8-4-1-2-7-11(8)18-15/h1-7,18,20,22H

Inchi Key: MGVCNALPOHOEQM-UHFFFAOYSA-N
Purity ≥ 98?% by NMR
Chemical Name 7-Bromoindirubin-3'-oxime
Formula C??H??BrN?O?
Permeability Cell-permeable
Background Synonyms: 7-Bromoindirubin-3'-oxime
Molecular Weight 356.2 g/mol
CAS-No 916440-85-2
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months