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  • 產(chǎn)品名稱(chēng)：Eltrombopag
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  • 產(chǎn)品型號(hào)：
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  • 產(chǎn)品廠商：Biovision
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  • 產(chǎn)品文檔：
                          
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            簡(jiǎn)單介紹：
        

        

            Eltrombopag
        

    


    

        

            詳情介紹：
        

        

            

                

                    
                        
                        
                    
                    
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                

                                                                                    
                                                Characteristics
                                            
                                        
                                                                                    
                                            
                                                
PubChem CID: 25181561
Molecular Formula: C??H??N?O?
Cell Premeable: Yes
Salt form: N/A
Eltrombopag is a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily.
Smiles: CC1=C(C=C(C=C1)N2C(=O)C(=C(N2)C)NN=C3C=CC=C(C3=O)C4=CC(=CC=C4)C(=O)O)C
InChi: InChI=1S/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,27-28H,1-3H3,(H,32,33)/b26-21-
Inchi Key: TYEXNVNUZXJNBN-QLYXXIJNSA-N

                                                                                            		
                                                                            

                                                                                                                                                                                                                                                            

                                                                                    
                                                Purity
                                            
                                        
                                                                                    
                                            
                                                ≥ 98?% by HPLC
                                                                                            
                                                                            

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    

                                                                                    
                                                Chemical Name
                                            
                                        
                                                                                    
                                            
                                                3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid; SB-497115; SB-497115-GR
                                                                                            
                                                                            

                                                                                                                                                                

                                                                                    
                                                Formula
                                            
                                        
                                                                                    
                                            
                                                C??H??N?O?
                                                                                            
                                                                            

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                

                                                                                    
                                                Permeability
                                            
                                        
                                                                                    
                                            
                                                Cell-permeable
                                                                                            
                                                                            

                                                                                                                                                                                                                                                                            
                    
                

            

                                                                        

                

                    
                        
                        
                    
                    
                                                                                                                                                                                                                                                                                                                                                                                                                                            

                                                                                    
                                                Background
                                            
                                        
                                                                                    
                                            
                                                Synonyms: 3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid, SB-497115, SB-497115-GR
                                                                                            
                                                                            

                                                                                                                                                                

                                                                                    
                                                Molecular Weight
                                            
                                        
                                                                                    
                                            
                                                442.47 g/mol
                                                                                            
                                                                            

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            

                                                                                    
                                                CAS-No
                                            
                                        
                                                                                    
                                            
                                                496775-61-2
                                                                                            
                                                                            

                                                                                                                                                                                                                                                                            
                    
                

            

                                                            

                

                    
                        
                        
                    
                    
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                

                                                                                    
                                                Restrictions
                                            
                                        
                                                                                    
                                            
                                                For Research Use only
                                                                                            
                                                                            

                                                                                    
                    
                

            

                                                                                                

                

                    
                        
                        
                    
                    
                                                                                                                                                        

                                                                                    
                                                Format
                                            
                                        
                                                                                    
                                            
                                                Solid
                                                                                            
                                                                            

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            

                                                                                    
                                                Handling Advice
                                            
                                        
                                                                                    
                                            
                                                Protect from air and light
                                                                                            
                                                                            

                                                                                                                                                                

                                                                                    
                                                Storage
                                            
                                        
                                                                                    
                                            
                                                -20 °C
                                                                                            
                                                                            

                                                                                                                                                                                                                                                            

                                                                                    
                                                Expiry Date
                                            
                                        
                                                                                    
                                            
                                                36 months