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  • 產品名稱:OxythiamineChlorideHydrochloride

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  • 產品廠商:Biovision
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簡單介紹:
OxythiamineChlorideHydrochloride
詳情介紹:
Characteristics

PubChem CID: 56845140
Molecular Formula: C??H??ClN?O?S.HCl
Cell Premeable: Yes

Salt form: No

Oxythiamine is a thiamine antagonist that acts as a transketolase inhibitor. As transketolase is a crucial enzyme of the pentose phosphate pathway, inhibition of this enzyme causes suppression of the pentose phosphate pathway and thus deprives cells of the metabolic intermediate (glyceraldehyde-3-phosphate) for ATP generation and of the substrates (NADPH, ribose-phosphate) for macromolecule synthesis. This metabolic inhibition seems to be responsible, at least in part, for the

Smiles: CC1=C(SC=[N+]1CC2=CN=C(N=C2N=O)C)CCO.Cl.[Cl-]

InChi: InChI=1S/C12H15N4O2S.2ClH/c1-8-11(3-4-17)19-7-16(8)6-10-5-13-9(2)14-12(10)15-18,/h5,7,17H,3-4,6H2,1-2H3,2*1H/q+1,/p-1

Inchi Key: BNURZUBKXXZBQE-UHFFFAOYSA-M

Purity ≥ 95?% by HPLC
Chemical Name 5-(2-Hydroxyethyl)-3-(4-hydroxy-2-methyl-5-pyrimidinylmethyl)-4-methylthiazolium chloride
Formula C??H??ClN?O?S.HCl
Permeability Cell-permeable
Background Synonyms: 5-(2-Hydroxyethyl)-3-(4-hydroxy-2-methyl-5-pyrimidinylmethyl)-4-methylthiazolium chloride
Molecular Weight 338.25 g/mol
CAS-No 614-05-1
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 36 months