產(chǎn)品詳情

  • 產(chǎn)品名稱：GSK-106hydrochloride

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
GSK-106hydrochloride
詳情介紹：
Characteristics

PubChem CID: N/A
Molecular Formula: C??H??ClN?O
Cell Premeable: Yes

Salt form: No

GSK-106 is a useful negative control for PAD4 inhibitors (GSK-121 and GSK-484). It does not inhibit PAD4 nor does it prevent the citrullination of PAD4 target proteins or the formation of neutrophil extracellular traps in mouse or human neutrophils (IC??s > 100 μM).

Smiles: O=C(N1CC(N)CCC1)C2=CC=C3C(N(C)C(C(N4CC)=CC5=C4C=CC=C5)=N3)=C2.[H]Cl

InChi: InChI=1S/C24H27N5O.ClH/c1-3-29-20-9-5-4-7-16(20)13-22(29)23-26-19-11-10-17(14-21(19)27(23)2)24(30)28-12-6-8-18(25)15-28,/h4-5,7,9-11,13-14,18H,3,6,8,12,15,25H2,1-2H3,1H

Inchi Key: VRPFLFUQMWOJAT-UHFFFAOYSA-N
Purity ≥ 98?%
Chemical Name (3-Aminopiperidin-1-yl)(2-(1-ethyl-1H-indol-2-yl)-1-methyl-1H-benzo[d]imidazol-6-yl)methanone hydrochloride
Formula C??H??ClN?O
Permeability Cell-permeable
Background Synonyms: (3-Aminopiperidin-1-yl)(2-(1-ethyl-1H-indol-2-yl)-1-methyl-1H-benzo[d]imidazol-6-yl)methanone hydrochloride
Molecular Weight 437.97 g/mol
CAS-No 1652591-82-6
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 36 months