產(chǎn)品詳情

  • 產(chǎn)品名稱：Lasofoxifenetartrate

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
Lasofoxifenetartrate
詳情介紹：
Characteristics

PubChem CID: 3081919
Molecular Formula: C??H??NO?.C?H?O?
Cell Premeable: Yes

Salt form: No

Lasofoxifene is a unique, non-steroidal selective estrogen receptor modulator (SERM). It selectively binds to human ERα with an IC?? value of 1.5 nM and inhibits bone loss in ovariectomized rats. Has potential use in treating breast cancer.

Smiles: C1CCN(C1)CCOC2=CC=C(C=C2)C3C(CCC4=C3C=CC(=C4)O)C5=CC=CC=C5.C(C(C(=O)O)O)(C(=O)O)O

InChi: InChI=1S/C28H31NO2.C4H6O6/c30-24-11-15-27-23(20-24)10-14-26(21-6-2-1-3-7-21)28(27)22-8-12-25(13-9-22)31-19-18-29-16-4-5-17-29,5-1(3(7)8)2(6)4(9)10/h1-3,6-9,11-13,15,20,26,28,30H,4-5,10,14,16-19H2,1-2,5-6H,(H,7,8)(H,9,10)/t26-,28+,1-,2-/m10/s1

Inchi Key: INEHJXCWEVNEDZ-LUDNRVPPSA-N
Purity ≥ 98?% by HPLC
Chemical Name (5R,6S)-5,6,7,8-tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol, (2S,3S)-2,3-dihydroxybutanedioate; CP-336,156
Formula C??H??NO?.C?H?O?
Permeability Cell-permeable
Background Synonyms: (5R,6S)-5,6,7,8-tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol, (2S,3S)-2,3-dihydroxybutanedioate, CP-336,156
Molecular Weight 563.6 g/mol
CAS-No 190791-29-8
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 36 months