Characteristics
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PubChem CID: 56845140 Molecular Formula: C??H??ClN?O?S.HCl Cell Premeable: Yes Salt form: No Oxythiamine is a thiamine antagonist that acts as a transketolase inhibitor. As transketolase is a crucial enzyme of the pentose phosphate pathway, inhibition of this enzyme causes suppression of the pentose phosphate pathway and thus deprives cells of the metabolic intermediate (glyceraldehyde-3-phosphate) for ATP generation and of the substrates (NADPH, ribose-phosphate) for macromolecule synthesis. This metabolic inhibition seems to be responsible, at least in part, for the Smiles: CC1=C(SC=[N+]1CC2=CN=C(N=C2N=O)C)CCO.Cl.[Cl-] InChi: InChI=1S/C12H15N4O2S.2ClH/c1-8-11(3-4-17)19-7-16(8)6-10-5-13-9(2)14-12(10)15-18,/h5,7,17H,3-4,6H2,1-2H3,2*1H/q+1,/p-1 Inchi Key: BNURZUBKXXZBQE-UHFFFAOYSA-M
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