產(chǎn)品詳情

  • 產(chǎn)品名稱：A-366

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
A-366
詳情介紹：
Purpose A potent and selective G9a/GLP histone lysine methyltransferase inhibitor
Characteristics A-366 is a potent and selective G9a/GLP histone lysine methyltransferase inhibitor (IC?? = 3.3 nM). It displays >1000-fold selectivity for G9a/GLP over 21 other methyltransferases. A-366 has been shown to inhibit H3K9 methylation in prostate cancer PC3 cells with an IC?? of 100 nM.
Purity ≥ 98?% by HPLC
Chemical Name 5'-Methoxy-6'-[3-(1-pyrrolidinyl)propoxy]spiro[cyclobutane-1,3'-[3H]indol]-2'-amine
Formula C??H??N?O?
Permeability Cell-permeable
Solubility DMSO (>25 mg/ml)
Molecular Weight 329.44 g/mol
CAS-No 1527503-11-2
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months