產(chǎn)品詳情

  • 產(chǎn)品名稱：NSC-319726

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
NSC-319726
詳情介紹：
Characteristics

PubChem CID: 5921672
Molecular Formula: C??H??N?S
Cell Premeable: Yes

Salt form: No

NSC-319726 is a reactivator of mutant p53. It restores WT structure and function to the p53(R175) mutant. NSC-319726 kills p53(R172H) knockin mice with extensive apoptosis and inhibits xenograft tumor growth in a 175-allele-specific mutant p53-dependent manner.

Smiles: CC(=NNC(=S)N1CCC1)C2=CC=CC=N2

InChi: InChI=1S/C11H14N4S/c1-9(10-5-2-3-6-12-10)13-14-11(16)15-7-4-8-15/h2-3,5-6H,4,7-8H2,1H3,(H,14,16)/b13-9-

Inchi Key: XDHBUMNIQRLHGO-LCYFTJDESA-N
Purity ≥ 98?%
Chemical Name 1-Azetidinecarbothioic acid [1-(2-pyridinyl)ethylidene]hydrazide
Formula C??H??N?S
Permeability Cell-permeable
Background Synonyms: 1-Azetidinecarbothioic acid [1-(2-pyridinyl)ethylidene]hydrazide
Molecular Weight 234.32 g/mol
CAS-No 71555-25-4
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months