產(chǎn)品詳情

  • 產(chǎn)品名稱：SNS-032

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
SNS-032
詳情介紹：
Characteristics

PubChem CID: 3025986
Molecular Formula: C??H??N?O?S?
Cell Premeable: Yes

Salt form: N/A

SNS-032 is a potent CDK inhibitor. Inhibits cyclin-dependent kinases (cdks) 9, 2 and 7 with IC?? values of 4, 38 and 62 nM respectively. Displays no activity against 190 additional kinases (IC?? >1000 nM). Prevents tumor cell-induced VEGF secretion and in vitro angiogenesis.

Smiles: CC(C)(C)C1=CN=C(O1)CSC2=CN=C(S2)NC(=O)C3CCNCC3

InChi: InChI=1S/C17H24N4O2S2/c1-17(2,3)12-8-19-13(23-12)10-24-14-9-20-16(25-14)21-15(22)11-4-6-18-7-5-11/h8-9,11,18H,4-7,10H2,1-3H3,(H,20,21,22)

Inchi Key: OUSFTKFNBAZUKL-UHFFFAOYSA-N
Purity ≥ 98?% by HPLC
Chemical Name N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide; BMS-387032
Formula C??H??N?O?S?
Permeability Cell-permeable
Background Synonyms: N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide, BMS-387032
Molecular Weight 380.53 g/mol
CAS-No 345627-80-7
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months