產(chǎn)品詳情

  • 產(chǎn)品名稱：BRD4770

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
BRD4770
詳情介紹：
Characteristics

PubChem CID: 72193870
Molecular Formula: C??H??N?O?
Cell Premeable: Yes

Salt form: No

BRD4770 is a selective inhibitor of the histone methyltransferase G9a (also named euchromatin histone methyltransferase 2 (EHMT2). BRD4770 blocks lysine residue 9 methylation of histone H3 without inducing apoptosis. In addition, it induces senescence, and inhibits both anchorage-dependent and -independent proliferation in the pancreatic cancer cell line PANC-1.

Smiles: COC(=O)C1=CC2=C(C=C1)N(C(=N2)NC(=O)C3=CC=CC=C3)CCCC4=CC=CC=C4

InChi: InChI=1S/C25H23N3O3/c1-31-24(30)20-14-15-22-21(17-20)26-25(27-23(29)19-12-6-3-7-13-19)28(22)16-8-11-18-9-4-2-5-10-18/h2-7,9-10,12-15,17H,8,11,16H2,1H3,(H,26,27,29)

Inchi Key: UCGWYCMPZXDHNR-UHFFFAOYSA-N
Purity ≥ 98?% by HPLC
Chemical Name Methyl 2-benzamido-1-(3-phenylpropyl)-1H-benzo[d]imidazole-5-carboxylate
Formula C??H??N?O?
Permeability Cell-permeable
Background Synonyms: Methyl 2-benzamido-1-(3-phenylpropyl)-1H-benzo[d]imidazole-5-carboxylate
Molecular Weight 413.47 g/mol
CAS-No 1374601-40-7
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months