產(chǎn)品詳情

  • 產(chǎn)品名稱：GSK-1059615

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
GSK-1059615
詳情介紹：
Characteristics

PubChem CID: 23582824
Molecular Formula: C??H??N?O?S
Cell Premeable: Yes

GSK-1059615 is a potent, reversible, ATP-competitive inhibitor of PI3Kα (IC?? = 2 nM). It inhibits proliferation in BT474 cells and attenuates MAPK signaling.

Smiles: C1=CC2=NC=CC(=C2C=C1C=C3C(=O)NC(=O)S3)C4=CC=NC=C4

InChi: InChI=1S/C18H11N3O2S/c22-17-16(24-18(23)21-17)10-11-1-2-15-14(9-11)13(5-8-20-15)12-3-6-19-7-4-12/h1-10H,(H,21,22,23)/b16-10-

Inchi Key: QDITZBLZQQZVEE-YBEGLDIGSA-N
Purity ≥ 98?% by HPLC
Chemical Name 5Z-?[[4-?(4-?pyridinyl)-?6-?quinolinyl]methylene]-?2,?4-?thiazolidinedione
Formula C??H??N?O?S
Permeability Cell-permeable
Background Synonyms: 5Z-?[[4-?(4-?pyridinyl)-?6-?quinolinyl]methylene]-?2,?4-?thiazolidinedione
Molecular Weight 333.36 g/mol
CAS-No 958852-01-2
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months