產(chǎn)品詳情

  • 產(chǎn)品名稱：Avasimibe

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
你添加了1件商品 查看購物車
簡單介紹：
Avasimibe
詳情介紹：
Characteristics

PubChem CID: 166558
Molecular Formula: C??H??NO?S
Cell Premeable: Yes

Salt form: No

Avasimibe is an orally bioavailable inhibitor of the acyl coenzyme A: cholesterol acyltransferase (ACAT) (IC?? = 60 nM). Avasimibe also inhibits major drug metabolizing enzymes such as CYP2C9 (IC?? = 2.9 μM ), CYP1A2 (IC?? = 13.9 μM), and CYP2C19 (IC?? = 26.5 μM).

Smiles: CC(C)C1=C(C(=CC=C1)C(C)C)OS(=O)(=O)NC(=O)CC2=C(C=C(C=C2C(C)C)C(C)C)C(C)C

InChi: InChI=1S/C29H43NO4S/c1-17(2)22-14-25(20(7)8)27(26(15-22)21(9)10)16-28(31)30-35(32,33)34-29-23(18(3)4)12-11-13-24(29)19(5)6/h11-15,17-21H,16H2,1-10H3,(H,30,31)

Inchi Key: PTQXTEKSNBVPQJ-UHFFFAOYSA-N
Purity ≥ 98?% by HPLC
Chemical Name [2,6-di(propan-2-yl)phenyl] N-[2-[2,4,6-tri(propan-2-yl)phenyl]acetyl]sulfamate; CI-1011; PD 148515
Formula C??H??NO?S
Permeability Cell-permeable
Background Synonyms: [2,6-di(propan-2-yl)phenyl] N-[2-[2,4,6-tri(propan-2-yl)phenyl]acetyl]sulfamate, CI-1011, PD 148515
Molecular Weight 501.72 g/mol
CAS-No 166518-60-1
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months