產(chǎn)品詳情

  • 產(chǎn)品名稱：UNC1215

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
UNC1215
詳情介紹：
Characteristics Cell-permeable. A potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3, a member of the malignant brain tumor (MBT) family of chromatin-interacting transcriptional repressors. It binds L3MBTL3 with a Kd value of 120 nM (IC50= 40 nM), competitively displacing mono- or dimethyl-lysine containing peptides. UNC1215 is > 50-fold selective toward L3MBTL3 than other members of the human MBT family and demonstrates selectivity against more than 200 other Kme reader domains examined.
Purity ≥ 98?% by HPLC
Chemical Name (2-?(Phenylamino)-?1,?4-?phenylene)bis((4-?(pyrrolidin-?1-?yl)piperidin-?1-?yl)methanone
Formula C??H??N?O?
Permeability Cell-permeable
Molecular Weight 529.72 g/mol
CAS-No 1415800-43-9
Restrictions For Research Use only
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for UNC 1215 (ABIN1685526) UNC 1215