產(chǎn)品詳情

  • 產(chǎn)品名稱：IWP-3

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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IWP-3
詳情介紹：
Characteristics An inhibitor of Wnt production. Blocks Wnt pathway activity in vitro (IC50= 40 nM). IWP-3 inactivates Porcupine (Porcn), a membrane-bound O-acyltransferase responsible for palmitoylating Wnt proteins, which is essential for their signaling ability and secretion. Through blockade of Wnt signaling, IWP-3 has been used to promote cardiomyocyte generation from human embryonic stem cells (EC50 = 1.2 μM).
Purity ≥ 98?%
Chemical Name Inhibitor of Wnt Production-3; 2-?[[3-?(4-?fluorophenyl)-?3,?4,?6,?7-?tetrahydro-?4-?oxothieno[3,?2-? d]pyrimidin-?2-?yl]thio]-?N-?(6-?methyl-?2-?benzothiazolyl)-?acetamide
Formula C??H??FN?O?S?
Permeability Cell-permeable
Molecular Weight 484.59 g/mol
CAS-No 687561-60-0
Restrictions For Research Use only
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months
Supplier Images
image for IWP-3 (ABIN1685724) IWP-3