產(chǎn)品詳情

  • 產(chǎn)品名稱：GSK-J4hydrochloride

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
GSK-J4hydrochloride
詳情介紹：
Characteristics Cell-permeable. An ethyl ester derivative of the JMJD3 selective histone demethylase inhibitor GSK-J1 (ABIN1685541, ABIN1685542) (IC50> 50 μM in vitro. When administered to human primary macrophages, GSK-J4 can reduce lipopolysaccharide (LPS)-induced proinflammatory cytokine production, most notably including that of TNFalpha (IC50= 9 μM).
Purity ≥ 95?%
Chemical Name Ethyl 3-?((6-?(4,?5-?dihydro-?1H-?benzo[d]azepin-?3(2H)-?yl)-?2-?-(pyridin-2- yl)pyrimidin-4-yl)amino)propanoate, monohydrochloride
Formula C??H??N?O? ? HCl
Permeability Cell-permeable
Molecular Weight 454.00 g/mol
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and mositure
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for GSK-J4 hydrochloride (ABIN1685539) GSK-J4 hydrochloride